First you need to be diagnosed with depression and have the symptoms of any kind of depression. If you tried treatment for your depression but symptoms never improved, you may have treatment-resistant depression. Taking an antidepressant or going to psychological counseling helps reduce symptoms for mamy people. But with treatment-resistant depression, standard treatments aren't enough. They may not help much at all, or may improve your symptoms, only for them to keep coming back. This shouldn't be confused with persistent depression, which requires you have had depression for at least two years [in a single span of time]. While many people with treatment resistant depression do have chronic or persistent depression, it typically isn't their main diagnosis. My personal experience is that medication does not help, from anxiety to depression to insomnia meds, and I've been in therapy for 6 years but it certainly hasnt relieved my symptoms to the point I...