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Ketamine Chronicles

 

Daily Sub-Dissociative Low-Dose Oral Dissolving Ketamine

Form: Lozenge
Minimum Dose: 20mg
Maximum Dose: 120mg

I was on this starting in 2021 and my last time doing Ketamine this way was December of 2024. It was the closest to taking a daily antidepressant out of the 3 ways I have tried it. I did not feel any active 'trip' phase or experience any dissociative effects. Overall, it gave me steady symptomatic relief, less emotional numbness, improved insomnia, better stress tolerance, lower anxiety and rumination. It is always more effective when paired with individual therapy, and regular self driven coping skill practice/self regulation.

Weekly/Bi-Weekly Guided Psychedelic/Dissociative Experience

Form: Oral Disintegrating Tablet
Minimum Dose: 200mg
Maximum Dose: 800mg
Duration: Active effects for 2 to 4 hours (followed by a 7 day period of increased neuroplasticity)

This has been my main treatment since January 2025 and it was life changing, and gave me high symptomatic relief and long stable periods of remission. The specific company I chose is really good and supplies a lot of guided meditations and journal prompts to help me get the most of the experience. There is a distinct active phase of the medication where there is a psychedelic experience with extremely vivid visuals. I have had a lot of realizations and revelations about life and myself during these. It has also allowed me to completely change how I mentally see my past and certain traumatic events. It makes connections I was not aware of that have been invisibly pushing my behavior for years. The way I connect my present and past has also rapidly changed. It has given me the courage and curiosity to deeply explore uncomfortable questions about life that I have been avoiding. After the 90 to 120 minute trip ends, there is still a sort of high for an hour or two. During this phase I feel intensely connected to my loved ones and other people in general. I feel a deep satisfaction and sense of contentment, and my rest feels rejuvenating and energizing. I feel motivatived, creative, and deeply inspired. What I do, see, and feel before and after this have a big impact on me so that has forced me to restructure and re-evaluate my life to be slow. mindful, intentional, and positive.

8 Week Spravato Nasal Spray Course

Form: Nasal Spray
Dose: 84 mg 
Duration: Active effects for 60 to 90 minutes (followed by a 7 day period of increased neuroplasticity)

I did this in the summer of 2025 although I only got half way through due to issues with the clinic I was recieving treatment. In the preparation materials the active period of this medication (the high which fades far faster than the neuroplastic window that gives Ketamine its true potential) was supposed to last last an hour or so and feel mildly trippy. I did not experience much during this phase besides 2 or 3 instances of vague geometric visuals. I listened to a guided meditation I picked before hand and also had a guided journal produced by Spravato which was surprisingly good. There was still marked differences in my thought patterns so thinking things through during this active phase was very productive. I experienced some mild nausea but no major side effects. While it was not a bad experience, this was not the best either it just felt like the light version of what I was doing before and after (weekly high dose oral)
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